Selected Publications

Published: (after line at the University of Toronto)

Refereed Journal Papers:

Lock R, Al Asafen H, Fleischer S, Tamargo M, Zhao Y, Radisic M, Vunjak-Novakovic G: “A framework for developing sex-specific engineered heart models”, Nature Reviews Materials, 1-19, 2021

Vunjak-Novakovic G, Ronaldson-Bouchard K, Radisic M: “Organs-on-a- chip models for biological research”, Cell, 84(18):4597-4611, 2021

Lai BFL, Lu RXZ, Davenport Huyer L, Kakinoki S, Yazbeck J, Wang EY, Wu Q, Zhang B, Radisic M: “A well-plate based multiplexed platform for incorporation of organoids into an organ-on-a-chip system with a perfusable vasculature”,  Nature Protocols, 1-32, March, 2021

Kuzmanov U, Wang EY, Vanderlaan R,  Guo H, Hadipour-Lakmehsari S, Zhao Y, Kim DH, Sharma P, Billia F, Radisic M, Gramolini A, Emili A: “Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources”, Nature Biomedical Engineering, 4, 9, 889-900, 2020

Davenport Huyer L, Mandla S, Wang Y, Yee B, Euler C, Lai BF, Bannerman D, Lin D SY, Montgomery M, Nemr K, Bender T, Epelman S, Mahadevan R, Radisic M: “Macrophage immunomodulation through new polymers that recapitulate functional effects of itaconate as a power house of innate immunity” Advanced Functional Materials, 31, 2003341, 2020

Lai BFL, Lu RXZ, Hu Y, Davenport Huyer L, Dou W, Wang EY, Radulovich N, Tsao MS, Sun Y, Radisic M: “Recapitulating pancreatic tumor microenvironment through synergistic use of patient organoids and organ-on-a-chip vasculature” Advanced Functional Materials, 30, 2000545, 2020

Davenport Huyer L, Pascual‐Gil S, Wang Y, Mandla S, Yee B, Radisic M: “Advanced Strategies for Modulation of the Material–Macrophage Interface” Advanced Functional Materials, https://doi.org/10.1002/adfm.201909331, 2020

Little M, Liu G-H, Shenoy KV, Vunjak-Novakovic G, Radisic M:  “Engineering Tissues and Organs: The Road to the Clinic” Cell, 181, 22-23, 2020

Xie R, Korolj A, Liu C, Song X,  Lu RXZ, Zhang B, Liang Q, Radisic M:  “h-FIBER: Microfluidic topographical hollow fiber for studies of glomerular filtration barrier” ACS Central Science, 6,6, 903-912, 2020 (cover paper)

Wang EY, Rafatian N, Zhao Y, Lee A, Lai BF, Lu X, Jekic D, Davenport Huyer L; Walden EJ, Bhattacharya S, Backx PH, Radisic M:  “Biowire model of interstitial and focal cardiac fibrosis” ACS  Central Science, 5, 1146-1158, 2019 (cover paper)

Zhao Y, Rafatian N, Feric NT, Aschar-Sobbi R, Zhang B, Wang EY, Conant G, Ronaldson K, Pahnke A, Protze S, Lee JH, Davenport-Huyer L, Jekic D, Keller GM, Vunjak-Novakovic G, Aggarwal P, Broeckel U, Backx PH, Radisic M: “A platform for generation of cardiac tissues with chamber-specific electrophysiological properties” Cell, 176:913-927, 2019

Zhang B, Korolj A, Lai BFL, Radisic M: “Advances in organ-on-a-chip engineering”, Nature Reviews Materials,  3: 257-278, 2018

Zhang B, Lai BFL, Xie R, Davenport-Huyer L, Montgomery M, Radisic M: “Microfabrication of AngioChip”, Nature Protocols, 13:1793-1813, 2018

Williams D, Edelman ER, Radisic M, Laurencin C, Untereker D “Engagement of the Medical Technology Sector with Society”, Science Translational Medicine, Science Translational Medicine, 8(342):342ps13, 2016

Lai BFL, Davenport-Huyer L, Lu RXZ, Drecun  S, Radisic M, Zhang B: “InVADE: Integrated Vasculature for Assessing Dynamic Events”, Advanced Functional Materials, 27:1703524, 2017

Montgomery M, Ahadian S, Lo Rito M,  Reis LA,  Davenport-Huyer L,  Akbari S, Vanderlaan R, Pahnke A, Caldarone CA, Radisic M: “Flexible Shape-memory Scaffold for Minimally Invasive Delivery of Functional Tissues”. Nature Materials, 16:1038-1046, 2017

Takebe T, Zhang B, Radisic M: “ Synergistic engineering: Organoids meet organs-on-a-chip “, Cell Stem Cell, 21:297-300, 2017

Xiao Y, Feric NT, Knee EJ, Gu J, Cao S, Laschinger C, Londono C, McGuigan AP,  Radisic M: “Diabetic wound regeneration using peptide-modified hydrogels targeting the epithelium”,  Proceedings of the National Academy of Sciences of the United States of America, 113(40):E5792-E5801, 2016

Zhang B, Montgomery M, Chamberlain MD, Ogawa S, Korolj A, Pahnke A, Wells LA, Massé S, Kim J, Reis L, Momen A, Nunes SS, Wheeler AR, Nanthakumar K, Keller G, Sefton MV, Radisic M: “Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis”, Nature Materials, 15:669-78, 2016

Ogle BM, Bursac N, Domian I, Huang NF, Menasche P, Murry C, Pruitt B, Radisic M, Wu J, Wu S, Zhang J, Zimmermann WH, Vunjak-Novakovic G: “Distilling Complexity to Advance Cardiac Tissue Engineering”, Science Translational Medicine, 8(342):342ps13, 2016

Zhang B, Montgomery M, Davenport-Huyer L, Korolj A, Radisic M.: “Platform technology for scalable assembly of instantaneously functional mosaic tissues.” Science Advances 1(7):e1500423, 2015

Liu H, Wen J, Xiao Y, Liu J, Hopyan S, Radisic M, Simmons CA, Sun Y : “In situ mechanical characterization of the cell nucleus by atomic force microscopy”, ACS Nano,  8:3821-8, 2014

Thavandiran N,  Dubois  D, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande V, McGarry P,  Chen CS, Nanthakumar K,  Keller G, Radisic M (co-corresponding author),  Zandstra PW: “Design criteria-guided formulation of pluripotent stem cell-derived cardiac microtissues”, Proceedings of the National Academy of Sciences of the United States of America  110(49):E4698-707. doi: 10.1073/pnas.1311120110 , 2013

Nunes SS, Miklas JW, Xiao Y, Zhang B, Hsieh A, Thavandiran N, Jiang J, Masse S, Ggaliardi M, Laflamme MA, Nanthakumar K, Gross G, Keller G, Radisic M: “Biowire: a platform for maturation of human pluripotent stem cell derived cardiomyocytes”, Nature Methods 10:781-787, 2013

Chiu LLY, Montgomery M, Liang Y, Liu H, Radisic M (corresponding author): “Perfusable branching microvessel bed for vascularization of engineered tissues”,  Proceedings of the National Academy of Sciences of the United States of America, 109:E3414-23, 2012

Leng L, McAllister A, Zhang B, Radisic M, Günther A: “Mosaic hydrogels: One-step formation ofmultidimensional, multiscale soft materials”,  Advanced Materials, 24:3650-8, 2012 (cover article)

Song H, Yoon C, Kattaman SJ,  Dengler J, Thavaratnam T, Gewarges M, Masse S,  Nanthakumar K, Rubart M, Keller GM, Radisic M, Zandstra P: “Interrogating functional integration between injected pluripotent stem cell derived-cells and surrogate cardiac tissue”, Proceedings of the National Academy of Sciences of the United States of America, 107:3329-3334, 2010

Tandon N, Cannizzaro C, Chao PH, Maidhof R, Marsano A, Au HT, Radisic M, Vunjak-Novakovic G. “Electrical stimulation systems for cardiac tissue engineering”, Nature Protocols, 4:155-173, 2009

Radisic M, Marsano A, Maidhof R, Wang Y, Vunjak-Novakovic G. “Cardiac tissue engineering using perfusion bioreactor systems” , Nature Protocols, 3:719-38, 2008

Radisic M , Park H, Shin H, Consi T, Schoen FJ, Freed LE, Vunjak-Novakovic G: “Functional assembly  of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds”,   Proceedings of the National Academy of Sciences of the United States of America, 101:18129-18134, Dec 28, 2004 (cover paper)